Emerging Biomarkers of Congenital Heart Diseases and Disorders

Congenital heart diseases are substantially appeared before or after birth. There are two important disease categories which are commonly appeared after birth vascular, congenital heart disease. Right ventricular hypertrophy is one of important congenital heart disease. These abnormalities are related to either structure or function of heart and also found associated to cardiovascular system. In principle these are recognizable in early life and are observed in 7-12 of every 1000 live births. But it is of all the trivial lesions which are recognized in early child hood. During infancy 50-60 per cent of these patients need medical and surgical help, among total non-treated patients only 10-15 per cent get survive without surgery to adolescence and adult life. These are known as natural survivors whose congenital defects or disease modify with the time and face post natal changes and remain abnormal. Prevalence of these diseases show lower child survival index that display basal infant and child mortality under the age of 5 years. Besides, children congenital heart diseases, adult congenital heart diseases are reported to increasing alarmingly. Though there are hundreds of congenital defects and few of them come in rare categories.